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CEACAM1 抗体 (AA 50-250)

The 小鼠 单克隆 anti-CEACAM1 antibody is suitable to detect CEACAM1 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7875345
发货至: 中国
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Quick Overview for CEACAM1 抗体 (AA 50-250) (ABIN7875345)

抗原

See all CEACAM1 抗体
CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

适用

  • 119
  • 24
  • 19
  • 4
  • 1

宿主

  • 79
  • 71
  • 5
  • 2
小鼠

克隆类型

  • 103
  • 54
单克隆

标记

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This CEACAM1 antibody is un-conjugated

应用范围

  • 82
  • 66
  • 50
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  • 24
  • 16
  • 9
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CEACAM1-4843
  • 抗原表位

    • 17
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-250

    原理

    BGP-1 Antibody / CEACAM1

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the BGP-1 antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the BGP-1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the BGP-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

    别名

    BGP-1

    背景

    Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), also known as BGP or BGP1 (Biliary glycoprotein 1), is a 526 amino acid protein that exists as seven alternatively spliced isoforms, some of which localize to the cell membranes, while others are secreted. One of several members of the CEACAM family, CEACAM1 contains one Ig-like V-type domain and three Ig-like C2-type domains and is thought to play a role in a variety of cellular activities, including angiogenesis, apoptosis, arrangement of tissue three dimensional structure and modulation of innate and adaptive immune responses. Additionally, CEACAM1 is under-expressed in colorectal cancers, suggesting a role in tumor suppression.

    UniProt

    P13688
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