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SOX11 抗体 (AA 50-200)

The 小鼠 单克隆 anti-SOX11 antibody is suitable to detect SOX11 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7875330
发货至: 中国
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Quick Overview for SOX11 抗体 (AA 50-200) (ABIN7875330)

抗原

See all SOX11 抗体
SOX11 (SRY (Sex Determining Region Y)-Box 11 (SOX11))

适用

  • 70
  • 33
  • 31
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 61
  • 9
  • 2
小鼠

克隆类型

  • 40
  • 32
单克隆

标记

  • 40
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
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  • 1
This SOX11 antibody is un-conjugated

应用范围

  • 45
  • 26
  • 14
  • 13
  • 13
  • 13
  • 8
  • 5
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

SOX11-7236
  • 抗原表位

    • 9
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-200

    原理

    SOX11 Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 50-200 was used as the immunogen for the SOX11 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the SOX11 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the SOX11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SOX11 (SRY (Sex Determining Region Y)-Box 11 (SOX11))

    别名

    SOX11

    背景

    Recognizes a protein of ~47 kDa, identified as SOX11. This MAb is highly specific and does not cross-react with other members of the SOX-family. Mantle cell lymphoma (MCL) accounts for 5 % to 10 % of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of Cyclin D1. Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5 %-10 % of MCLs lack Cyclin D1 expression and may be misdiagnosed. Almost all Cyclin D1-positive as well as Cyclin D1-negative MCL, show overexpression of SOX-11. The detection of this transcription factor is a useful biomarker for identifying true cyclin D1-negative MCL.

    UniProt

    P35716

    途径

    Tube Formation
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