Peroxiredoxin 2 抗体 (AA 5-127)
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Quick Overview for Peroxiredoxin 2 抗体 (AA 5-127) (ABIN7875288)
抗原
See all Peroxiredoxin 2 (PRDX2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-127
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原理
- PRDX2 Antibody / Peroxiredoxin 2
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids N5-R127) was used as the immunogen for the PRDX2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PRDX2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PRDX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Peroxiredoxin 2 (PRDX2)
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别名
- PRDX2
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背景
- PRDX2 (Peroxiredoxin 2) also known as NKEFB, PRP, PRX2, PRXII or TPX1, is a protein that in humans is encoded by the PRDX2 gene. This gene encodes a member of the peroxiredoxin family of anti-oxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The Prdx2-/- mice were healthy in appearance and fertile. Choi et al.(2005) demonstrated that PRDX2 is a negative regulator of PDGF signaling. Prx II deficiency results in increased production of peroxide, enhanced activation of PDGF receptor and phospholipase C-gamma-1, and subsequently increased cell proliferation and migration in response to PDGF. PRX2 accounted for about half of the thioredoxin activity in parasite extracts, and PRX2 expression was increased in the presence of chloroquine, regardless of P. falciparum strain susceptibility to the drug.
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UniProt
- P32119
抗原
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