Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 498-804) 抗体
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Quick Overview for Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 498-804) 抗体 (ABIN7875284)
抗原
See all Protocadherin gamma Subfamily C, 3 (PCDHGC3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 498-804
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原理
- PCDHGC3 Antibody / Protocadherin gamma C3
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids E498-E804) was used as the immunogen for the PCDHGC3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PCDHGC3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PCDHGC3 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Protocadherin gamma Subfamily C, 3 (PCDHGC3)
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别名
- PCDHGC3
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背景
- Protocadherin gamma-C3 is a protein that in humans is encoded by the PCDHGC3 gene. This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
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UniProt
- Q9UN70
抗原
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