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TNK2 抗体 (AA 491-1038)

This 兔 多克隆 antibody specifically detects TNK2 in WB, ELISA 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7875263
发货至: 中国
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Quick Overview for TNK2 抗体 (AA 491-1038) (ABIN7875263)

抗原

See all TNK2 抗体
TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

适用

  • 120
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宿主

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  • 1

克隆类型

  • 119
  • 1
多克隆

标记

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This TNK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 26
    • 15
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    AA 491-1038

    原理

    Activated CDC42 kinase 1 Antibody / ACK1

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids M491-R1038) was used as the immunogen for the Activated CDC42 kinase 1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Activated CDC42 kinase 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Activated CDC42 kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

    别名

    Activated CDC42 kinase 1

    背景

    Activated CDC42 kinase 1, also known as ACK1, is an enzyme that in humans is encoded by the TNK2 gene. This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

    UniProt

    Q07912
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