Mps1 抗体 (AA 487-821)
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Quick Overview for Mps1 抗体 (AA 487-821) (ABIN7875232)
抗原
See all Mps1 (TTK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 487-821
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原理
- TTK Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids Q487-S821) was used as the immunogen for the TTK antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TTK antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TTK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Mps1 (TTK)
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别名
- TTK
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背景
- Dual specificity protein kinase TTK is a protein that in humans is encoded by the TTK gene. This gene is mapped to 6q14.1. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
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UniProt
- P33981
抗原
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