BIRC6 抗体 (AA 4810-4844)
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北京 101111
Quick Overview for BIRC6 抗体 (AA 4810-4844) (ABIN7875225)
抗原
See all BIRC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4810-4844
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原理
- BIRC6 Antibody (C-Terminal Region)
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 4810-4844 from human BIRC6 was used as the immunogen for the BIRC6 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the BIRC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the BIRC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
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别名
- BIRC6
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背景
- Baculoviral IAP repeat-containing protein 6 / APOLLON is an anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification. [UniProt]
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UniProt
- Q9NR09
抗原
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