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BIRC6 抗体 (AA 4810-4844)

The 兔 多克隆 anti-BIRC6 antibody is suitable to detect BIRC6 in samples from 人. It has been validated for WB.
产品编号 ABIN7875225
发货至: 中国
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Quick Overview for BIRC6 抗体 (AA 4810-4844) (ABIN7875225)

抗原

See all BIRC6 抗体
BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

适用

  • 26
  • 3
  • 1

宿主

  • 24
  • 2

克隆类型

  • 26
多克隆

标记

  • 14
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BIRC6 antibody is un-conjugated

应用范围

  • 12
  • 12
  • 7
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4810-4844

    原理

    BIRC6 Antibody (C-Terminal Region)

    纯化方法

    Antigen affinity

    免疫原

    A portion of amino acids 4810-4844 from human BIRC6 was used as the immunogen for the BIRC6 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the BIRC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the BIRC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

    别名

    BIRC6

    背景

    Baculoviral IAP repeat-containing protein 6 / APOLLON is an anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification. [UniProt]

    UniProt

    Q9NR09
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