MAPK8IP1 抗体 (AA 470-498)
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Quick Overview for MAPK8IP1 抗体 (AA 470-498) (ABIN7875168)
抗原
See all MAPK8IP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 470-498
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原理
- MAPK8IP1 Antibody / JIP1
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 470-498 from the human protein was used as the immunogen for the MAPK8IP1 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the MAPK8IP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MAPK8IP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
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别名
- MAPK8IP1
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背景
- JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.
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UniProt
- Q9UQF2
抗原
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