RGMB 抗体 (AA 47-404)
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Quick Overview for RGMB 抗体 (AA 47-404) (ABIN7875162)
抗原
See all RGMB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 47-404
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原理
- RGMB Antibody / Repulsive Guidance Molecule B
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids D47-R404) was used as the immunogen for the RGMB antibody.
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亚型
- IgG
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anti-RGM Domain Family, Member B (RGMB) antibody
RGMB 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB56812 unconjugated
anti-RGM Domain Family, Member B (RGMB) (Center) antibodyRGMB 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RGM Domain Family, Member B (RGMB) (AA 376-406), (C-Term) antibodyRGMB 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RGM Domain Family, Member B (RGMB) (AA 380-407), (C-Term) antibodyRGMB 适用: 人 WB 宿主: 兔 Polyclonal RB37543 unconjugated
anti-RGM Domain Family, Member B (RGMB) (AA 47-404) antibodyRGMB 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the RGMB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RGMB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RGMB (RGM Domain Family, Member B (RGMB))
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别名
- RGMB
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背景
- Repulsive guidance molecule B (RGMb), also known as DRAGON (DRG11-responsive axonal guidance and outgrowth of neurite), is a bone morphogenetic protein (BMP) co-receptor of the repulsive guidance molecule family. In humans this protein is encoded by the RGMB gene. RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see also RGMA and RGMC) and contributes to the patterning of the developing nervous system. There is a potential association between RGMs and cancer bone metastasis, as RGMs coordinate bone morphogenetic protein (BMP) signaling. RGMB may act as a negative regulator in vitro in breast cancer and prostate cancer through BMP signalling. Furthermore, aberrant expression of RGMs was indicated in breast cancer. The perturbed expression was associated with disease progression and poor prognosis.
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UniProt
- Q6NW40
抗原
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