AMH 抗体 (C-Term)
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北京 101111
Quick Overview for AMH 抗体 (C-Term) (ABIN7875132)
抗原
See all AMH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 460-560, C-Term
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原理
- Anti Mullerian Hormone Antibody / AMH
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment of the C-terminus of the human protein (within amino acids 460-560) was used as the immunogen for the Anti Mullerian Hormone antibody.
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亚型
- IgG1, kappa
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anti-Anti-Mullerian Hormone (AMH) (AA 447-553) antibody
AMH 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Anti-Mullerian Hormone (AMH) antibodyAMH 适用: 斑马鱼 WB, IHC 宿主: 小鼠 Monoclonal C6 unconjugated
anti-Anti-Mullerian Hormone (AMH) (AA 26-560) antibodyAMH 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Anti-Mullerian Hormone (AMH) (AA 424-451) antibodyAMH 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Anti-Mullerian Hormone (AMH) (AA 453-560) antibodyAMH 适用: 人 WB 宿主: 小鼠 Monoclonal 4-1# unconjugated
anti-Anti-Mullerian Hormone (AMH) (AA 424-451) antibodyAMH 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Anti-Mullerian Hormone (AMH) (AA 430-460), (Middle Region) antibodyAMH 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Anti-Mullerian Hormone (AMH) (AA 409-644) antibodyAMH 适用: 小鸡 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Anti-Mullerian Hormone (AMH) (AA 19-560) antibodyAMH 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal J17 unconjugated
anti-Anti-Mullerian Hormone (AMH) (AA 468-517) antibodyAMH 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 豚鼠, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Anti Mullerian Hormone antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Anti Mullerian Hormone antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- AMH (Anti-Mullerian Hormone (AMH))
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别名
- Anti Mullerian Hormone
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背景
- The transforming growth factor beta (TGF beta) superfamily is composed of numerous growth and differentiation factors, including TGF beta1-3, Mullerian inhibiting substance (MIS), growth/differentiation factor (GDF) 1-9, bone morphogenic protein (BMP) 2-8, glial cell line-derived neurotrophic factor (GDNF), Inhibin Alpha, beta-A, beta-B and beta-C, Lefty and Nodal. Members of the TGF beta superfamily are involved in embryonic development and adult tissue homeostasis. The MIS glycoprotein is produced by the Sertoli cells of the testes. Fetal testes produce both MIS and testosterone, the presence of which result in male offspring. Absence of MIS and testosterone in a developing fetus results in the induction of Mullerian duct differentiation, and Wolffian duct development is not induced. Testosterone induces the differentiation of the Wolffian ducts whereas MIS causes regression of the Muellerian duct. MIS inhibits the growth of tumors derived from tissues of Mullerian duct origin. MIS can also inhibit the autophosphorylation of the EGF receptor in vitro. Defects in anti-Muellerian hormone are the cause of persistent Muellerian duct syndrome type I (PMDS-1). PMDS-1 is a form of male pseudo hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
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UniProt
- P03971
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途径
- Negative Regulation of Hormone Secretion
抗原
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