Dynamin 1-Like 抗体 (AA 452-736)
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Quick Overview for Dynamin 1-Like 抗体 (AA 452-736) (ABIN7875098)
抗原
See all Dynamin 1-Like (DNM1L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 452-736
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原理
- Dynamin-1-like protein Antibody / DNM1L / DRP1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids Q452-W736) was used as the immunogen for the Dynamin-1-like protein antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Dynamin-1-like protein antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Dynamin-1-like protein antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Dynamin 1-Like (DNM1L)
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别名
- Dynamin-1-like protein
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背景
- Dynamin-1-like protein is a GTPase that regulates mitochondrial fission. In humans, dynamin-1-like protein, which is typically referred to as dynamin-related protein 1 (Drp1), is encoded by the DNM1L gene. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- O00429
抗原
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