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Filamin A 抗体 (AA 451-638)

The 兔 多克隆 anti-Filamin A antibody is suitable to detect Filamin A in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF, IHC (p) 和 FACS.
产品编号 ABIN7875096
发货至: 中国
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Quick Overview for Filamin A 抗体 (AA 451-638) (ABIN7875096)

抗原

See all Filamin A (FLNA) 抗体
Filamin A (FLNA) (Filamin A, alpha (FLNA))

适用

  • 119
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  • 1
人, 小鼠, 大鼠

宿主

  • 108
  • 11
  • 1

克隆类型

  • 86
  • 34
多克隆

标记

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This Filamin A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

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    AA 451-638

    原理

    Filamin A Antibody

    纯化方法

    Affinity purified

    免疫原

    A human recombinant protein (amino acids E451-Q638) was used as the immunogen for the Filamin A antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Filamin A antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Filamin A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Filamin A (FLNA) (Filamin A, alpha (FLNA))

    别名

    Filamin A

    背景

    Filamin A, alpha (FLNA) is a protein that in humans is encoded by the FLNA gene. It is mapped to Xq28. The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

    UniProt

    P21333

    途径

    TCR Signaling, Maintenance of Protein Location
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