Filamin A 抗体 (AA 451-638)
Our Local Distributor
北京 101111
Quick Overview for Filamin A 抗体 (AA 451-638) (ABIN7875095)
抗原
See all Filamin A (FLNA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 451-638
-
原理
- FLNA Antibody / Filamin A
-
纯化方法
- Affinity purified
-
免疫原
- A human recombinant partial protein (amino acids E451-Q638) was used as the immunogen for the FLNA antibody.
-
亚型
- IgG1
-
-
-
-
应用备注
- Optimal dilution of the FLNA antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the FLNA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Filamin A (FLNA) (Filamin A, alpha (FLNA))
-
别名
- FLNA
-
背景
- Filamin A, alpha (FLNA) is a protein that in humans is encoded by the FLNA gene. It is mapped to Xq28. The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
-
UniProt
- P21333
-
途径
- TCR Signaling, Maintenance of Protein Location
抗原
-