ACPL2 抗体 (AA 45-459)
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Quick Overview for ACPL2 抗体 (AA 45-459) (ABIN7875074)
抗原
See all ACPL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-459
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原理
- PXYLP1 Antibody / 2-Phosphoxylose phosphatase 1
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids K45-D459) was used as the immunogen for the PXYLP1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PXYLP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PXYLP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ACPL2 (Acid Phosphatase-Like 2 (ACPL2))
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别名
- PXYLP1
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背景
- PXYLP1 dephosphorylates the xylose (xyl) residue in the glycosaminoglycan (GAG)-protein linkage region of proteoglycans, which is required for biosynthetic maturation of the linkage region. Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.
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UniProt
- Q8TE99
抗原
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