PRR5 抗体 (AA 45-366)
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Quick Overview for PRR5 抗体 (AA 45-366) (ABIN7875069)
抗原
See all PRR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-366
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原理
- Protor-1 Antibody / Protein observed with Rictor-1 / PRR5
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids S45-D366) was used as the immunogen for the Protor-1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Protor-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Protor-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PRR5 (Proline Rich 5 (Renal) (PRR5))
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别名
- Protor-1
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背景
- This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
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UniProt
- P85299
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途径
- PI3K-Akt Signaling
抗原
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