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PRR5 抗体 (AA 45-366)

The 兔 多克隆 anti-PRR5 antibody is suitable to detect PRR5 in samples from 人. It has been validated for WB, ELISA 和 FACS.
产品编号 ABIN7875069
发货至: 中国
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Quick Overview for PRR5 抗体 (AA 45-366) (ABIN7875069)

抗原

See all PRR5 抗体
PRR5 (Proline Rich 5 (Renal) (PRR5))

适用

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宿主

  • 44

克隆类型

  • 44
多克隆

标记

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This PRR5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 45-366

    原理

    Protor-1 Antibody / Protein observed with Rictor-1 / PRR5

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids S45-D366) was used as the immunogen for the Protor-1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Protor-1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Protor-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    PRR5 (Proline Rich 5 (Renal) (PRR5))

    别名

    Protor-1

    背景

    This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.

    UniProt

    P85299

    途径

    PI3K-Akt Signaling
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