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ChT 抗体 (AA 446-580)

The 兔 多克隆 anti-ChT antibody (ABIN7875049) specifically detects ChT in WB, FACS 和 ELISA. The antibody is reactive with 小鼠, 人 和 大鼠 samples.
产品编号 ABIN7875049
发货至: 中国
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Quick Overview for ChT 抗体 (AA 446-580) (ABIN7875049)

抗原

See all ChT 抗体
ChT (High Affinity Choline Transporter (ChT))

适用

  • 13
  • 11
  • 11
  • 9
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
小鼠, 人, 大鼠

宿主

  • 12
  • 9
  • 1

克隆类型

  • 13
  • 9
多克隆

标记

  • 16
  • 2
  • 2
  • 2
This ChT antibody is un-conjugated

应用范围

  • 12
  • 9
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), ELISA
  • 抗原表位

    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 446-580

    原理

    SLC5A7 Antibody / High affinity choline transporter 1

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids R446-Q580) was used as the immunogen for the SLC5A7 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the SLC5A7 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the SLC5A7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ChT (High Affinity Choline Transporter (ChT))

    别名

    SLC5A7

    背景

    The high-affinity choline transporter (ChT) also known as solute carrier family 5 member 7 is a protein in humans that is encoded by the SLC5A7 gene. This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.

    UniProt

    Q9GZV3
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