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CLPB 抗体 (AA 438-707)

The 兔 多克隆 anti-CLPB antibody is suitable to detect CLPB in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC (p), FACS 和 IF.
产品编号 ABIN7875000
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CLPB 抗体 (AA 438-707) (ABIN7875000)

抗原

See all CLPB 抗体
CLPB (ClpB Caseinolytic Peptidase B Homolog (CLPB))

适用

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人, 小鼠, 大鼠

宿主

  • 26
  • 1

克隆类型

  • 27
多克隆

标记

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This CLPB antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
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    AA 438-707

    原理

    CLPB Antibody / Caseinolytic peptidase B protein

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids Q438-I707) was used as the immunogen for the CLPB antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CLPB antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the CLPB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    CLPB (ClpB Caseinolytic Peptidase B Homolog (CLPB))

    别名

    CLPB

    背景

    This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants.

    UniProt

    Q9H078
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