CLPB 抗体 (AA 438-707)
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Quick Overview for CLPB 抗体 (AA 438-707) (ABIN7875000)
抗原
See all CLPB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 438-707
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原理
- CLPB Antibody / Caseinolytic peptidase B protein
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids Q438-I707) was used as the immunogen for the CLPB antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CLPB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CLPB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CLPB (ClpB Caseinolytic Peptidase B Homolog (CLPB))
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别名
- CLPB
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背景
- This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants.
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UniProt
- Q9H078
抗原
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