DHCR7 抗体 (AA 437-463)
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北京 101111
Quick Overview for DHCR7 抗体 (AA 437-463) (ABIN7874996)
抗原
See all DHCR7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 437-463
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原理
- DHCR7 Antibody / 7-dehydrocholesterol reductase
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 437-463 from the human protein was used as the immunogen for the DHCR7 antibody.
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亚型
- Ig Fraction
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anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 437-463), (C-Term) antibody
DHCR7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17942 unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 1-475) antibodyDHCR7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 63-147) antibodyDHCR7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 351-450) antibodyDHCR7 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the DHCR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the DHCR7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))
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别名
- DHCR7
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背景
- This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS), a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.
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UniProt
- Q9UBM7
抗原
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