Transglutaminase 2 抗体 (AA 429-458)
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Quick Overview for Transglutaminase 2 抗体 (AA 429-458) (ABIN7874943)
抗原
See all Transglutaminase 2 (TGM2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 429-458
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原理
- Protein-glutamine gamma-glutamyltransferase 2 Antibody / Transglutaminase 2
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纯化方法
- Purified
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免疫原
- A portion of amino acids 429-458 from the human protein was used as the immunogen for the Protein-glutamine gamma-glutamyltransferase 2 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Protein-glutamine gamma-glutamyltransferase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Protein-glutamine gamma-glutamyltransferase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
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别名
- Protein-glutamine gamma-glutamyltransferase 2
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背景
- Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.
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UniProt
- P21980
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途径
- Tube Formation, Thromboxane A2 Receptor Signaling
抗原
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