SHROOM2 抗体 (AA 427-1138)
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Quick Overview for SHROOM2 抗体 (AA 427-1138) (ABIN7874940)
抗原
See all SHROOM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 427-1138
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原理
- SHROOM2 Antibody / APXL
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R427-H1138) was used as the immunogen for the SHROOM2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SHROOM2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SHROOM2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SHROOM2 (Shroom Family Member 2 (SHROOM2))
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别名
- SHROOM2
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背景
- Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene. This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene.
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UniProt
- Q13796
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途径
- Cell-Cell Junction Organization, Asymmetric Protein Localization
抗原
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