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IGF2R 抗体 (AA 424-529)

The 小鼠 单克隆 anti-IGF2R antibody (Clone 4I11) (ABIN7874935) specifically detects IGF2R in WB, FACS, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7874935
发货至: 中国
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Quick Overview for IGF2R 抗体 (AA 424-529) (ABIN7874935)

抗原

See all IGF2R 抗体
IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

适用

  • 91
  • 36
  • 13
  • 8
  • 5
  • 3
  • 2
  • 1
  • 1

宿主

  • 65
  • 36
小鼠

克隆类型

  • 60
  • 41
单克隆

标记

  • 56
  • 7
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  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
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This IGF2R antibody is un-conjugated

应用范围

  • 44
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  • 17
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  • 11
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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

4I11
  • 抗原表位

    • 16
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
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    • 1
    • 1
    AA 424-529

    原理

    IGF2R Antibody / M6PR

    纯化方法

    Affinity purified

    免疫原

    An E. coli-derived human protein (amino acids F424-R529) was used as the immunogen for the IGF2R antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the IGF2R antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the IGF2R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

    别名

    IGF2R

    背景

    Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

    UniProt

    P11717
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