IGF2R 抗体 (AA 424-529)
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Quick Overview for IGF2R 抗体 (AA 424-529) (ABIN7874935)
抗原
See all IGF2R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 424-529
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原理
- IGF2R Antibody / M6PR
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived human protein (amino acids F424-R529) was used as the immunogen for the IGF2R antibody.
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亚型
- IgG2a
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应用备注
- Optimal dilution of the IGF2R antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the IGF2R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
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别名
- IGF2R
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背景
- Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
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UniProt
- P11717
抗原
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