STIM1 抗体 (AA 42-599)
Our Local Distributor
北京 101111
Quick Overview for STIM1 抗体 (AA 42-599) (ABIN7874927)
抗原
See all STIM1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 42-599
-
原理
- STIM1 Antibody
-
纯化方法
- Antigen affinity chromatography
-
免疫原
- An E.coli-derived human recombinant protein (amino acids E42-L599) was used as the immunogen for the STIM1 antibody.
-
亚型
- IgG
-
-
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-685) antibody
STIM1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 1-211) antibodySTIM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (C-Term) antibodySTIM1 适用: 人, 大鼠, 小鼠 WB, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal CDN3H4 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) antibodyKD Validated STIM1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2415 unconjugated Recombinant Antibody
anti-Stromal Interaction Molecule 1 (STIM1) (AA 45-74), (N-Term) antibodySTIM1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 56-69), (Extracellular) antibodyKO Validated STIM1 适用: 人 WB, IHC, IP, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-686) antibodySTIM1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-686) antibodySTIM1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 509-538), (C-Term) antibodySTIM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19222 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 56-69), (Extracellular) antibody (Atto 550)STIM1 适用: 人 IHC, IF, FACS, IC, LCI 宿主: 兔 Polyclonal Atto 550
-
-
应用备注
- Optimal dilution of the STIM1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the STIM1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- STIM1 (Stromal Interaction Molecule 1 (STIM1))
-
别名
- STIM1
-
背景
- Stromal interaction molecule 1 is a protein that in humans is encoded by the STIM1 gene. STIM1 has a single transmembranedomain, and is localized to the endoplasmic reticulum, and to a lesser extent to the plasma membrane. This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants.
-
UniProt
- Q13586
-
途径
- TCR Signaling, BCR Signaling
抗原
-
