HSD17B8 抗体 (AA 42-244)
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Quick Overview for HSD17B8 抗体 (AA 42-244) (ABIN7874918)
抗原
See all HSD17B8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 42-244
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原理
- HSD17B8 Antibody / 17-beta-hydroxysteroid dehydrogenase 8
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids D42-D244) was used as the immunogen for the HSD17B8 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the HSD17B8 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HSD17B8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
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别名
- HSD17B8
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背景
- Estradiol 17 beta-dehydrogenase 8, also called 17-beta-HSD 8 and Protein Ke6, is an enzyme that in humans is encoded by the HSD17B8 gene. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
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UniProt
- Q92506
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途径
- Steroid Hormone Biosynthesis
抗原
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