ADAM15 抗体 (AA 41-456)
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Quick Overview for ADAM15 抗体 (AA 41-456) (ABIN7874840)
抗原
See all ADAM15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-456
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原理
- ADAM15 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids R41-R456) was used as the immunogen for the ADAM15 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ADAM15 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ADAM15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
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别名
- ADAM15
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背景
- Disintegrin and metalloproteinase domain-containing protein 15 is an enzyme that in humans is encoded by the ADAM15 gene. This gene is mapped to 1q21.3. The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
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UniProt
- Q13444
抗原
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