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MX1 抗体 (AA 400-592)

This 小鼠 单克隆 antibody specifically detects MX1 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7874735
发货至: 中国
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Quick Overview for MX1 抗体 (AA 400-592) (ABIN7874735)

抗原

See all MX1 抗体
MX1 (Myxovirus Resistance Protein 1 (MX1))

适用

  • 86
  • 19
  • 13
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 64
  • 33
  • 1
小鼠

克隆类型

  • 66
  • 32
单克隆

标记

  • 57
  • 12
  • 9
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This MX1 antibody is un-conjugated

应用范围

  • 69
  • 32
  • 32
  • 13
  • 10
  • 8
  • 8
  • 6
  • 4
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

MX1-7530
  • 抗原表位

    • 11
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-592

    原理

    Myxovirus resistance protein 1 Antibody / MX1 / MxA (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 400-592) from the human protein was used as the immunogen for the Myxovirus resistance protein 1 antibody.

    亚型

    IgG2, kappa
  • 应用备注

    Optimal dilution of the Myxovirus resistance protein 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Myxovirus resistance protein 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MX1 (Myxovirus Resistance Protein 1 (MX1))

    别名

    Myxovirus resistance protein 1

    背景

    The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx2 (myxovirus resistance protein 2) and Mx1 (myxovirus resistance protein 1) are members of the Dynamin family that are involved in the immune response to viral infections. Localized to the cytoplasm, Mx2 contains one GED domain and is expressed in response to viral infection or treatment by IFN-a/IFN-b. Once expression is induced, Mx2 accumulates in the cytoplasm and inhibits the replication of vesicular stomatitis virus (VSV), thereby conferring resistance to VSV infection. Unlike Mx2, Mx1 is localized to the nucleus where, upon induction by IFN-a/IFN-b, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family.

    UniProt

    P20591
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