GIT2 抗体 (AA 400-556)
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Quick Overview for GIT2 抗体 (AA 400-556) (ABIN7874728)
抗原
See all GIT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-556
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原理
- GIT2 Antibody / GRK-interacting protein 2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids D400-S556) was used as the immunogen for the GIT2 antibody.
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亚型
- IgG
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anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibody
GIT2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B5-B9 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal M1 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (Internal Region) antibodyGIT2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 401-498) antibodyGIT2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-603) antibodyGIT2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (Internal Region) antibodyGIT2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 714-749), (C-Term) antibodyGIT2 适用: 人 WB 宿主: 兔 Polyclonal RB48356 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-312) antibodyGIT2 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the GIT2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the GIT2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
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别名
- GIT2
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背景
- ARF GTPase-activating protein GIT2 is an enzyme that in humans is encoded by the GIT2 gene. This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.
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UniProt
- Q14161
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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