NSF 抗体 (AA 4-636)
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北京 101111
Quick Overview for NSF 抗体 (AA 4-636) (ABIN7874683)
抗原
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宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-636
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原理
- Vesicle-fusing ATPase Antibody / NSF
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids R4-Q636) was used as the immunogen for the Vesicle-fusing ATPase antibody.
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亚型
- IgG
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anti-N-Ethylmaleimide-Sensitive Factor (NSF) (AA 590-744) antibody
NSF 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor (NSF) (AA 620-744) antibodyNSF 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor (NSF) (AA 1-250) antibodyNSF 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor (NSF) (AA 1-744) antibodyNSF 适用: 大鼠, 小鼠 WB, ELISA, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal 83-11 unconjugated
anti-N-Ethylmaleimide-Sensitive Factor (NSF) (AA 668-696), (C-Term) antibodyNSF 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB41933 unconjugated
anti-N-Ethylmaleimide-Sensitive Factor (NSF) (Internal Region) antibodyNSF 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor (NSF) (C-Term) antibodyNSF 适用: 人, 大鼠, 小鼠, Cow, Pig, 兔, 犬, 马, 斑马鱼, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor (NSF) (AA 733-744) antibodyNSF 适用: 人, 大鼠, 小鼠, Hamster WB, ELISA, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor (NSF) (AA 1-744) antibodyNSF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor (NSF) (AA 1-744) antibodyNSF 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Vesicle-fusing ATPase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Vesicle-fusing ATPase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NSF (N-Ethylmaleimide-Sensitive Factor (NSF))
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别名
- Vesicle-fusing ATPase
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背景
- N-ethylmaleimide-sensitive factor, also known as NSF and Vesicle-fusing ATPase, is an enzyme which in humans is encoded by the NSF gene. NSF is a homohexameric AAA ATPase involved in membrane fusion. NSF is ubiquitously found in the cytoplasm of eukaryotic cells. It is a central component of the cellular machinery in the transfer of membrane vesicles from one membrane compartment to another. During this process, SNARE proteins on two joining membranes (usually a vesicle and a target membrane such as the plasma membrane) form a tight complex. This aids fusion of the vesicle with the target membrane. It has been proposed that the role of NSF is to undo these SNARE complexes once membrane fusion has occurred, using the hydrolysis of ATP as an energy source, allowing the dissociated SNAREs to be recycled for reuse in further rounds of membrane fusion. This proposal remains controversial, however. Recent work indicates that the ATPase function of NSF does not function in recycling of vesicles but rather functions in the act of fusing vesicles with the plasma membrane.
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UniProt
- P46459
抗原
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