MED17 抗体 (AA 4-561)
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Quick Overview for MED17 抗体 (AA 4-561) (ABIN7874682)
抗原
See all MED17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-561
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原理
- MED17 Antibody / Trap80 / ARC77
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (V4-E561) was used as the immunogen for the MED17 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MED17 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MED17 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MED17 (Mediator Complex Subunit 17 (MED17))
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别名
- MED17
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背景
- Mediator of RNA polymerase II transcription subunit 17 is an enzyme that in humans is encoded by the MED17 gene. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
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UniProt
- Q9NVC6
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
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