MARCH5 抗体 (AA 4-32)
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Quick Overview for MARCH5 抗体 (AA 4-32) (ABIN7874670)
抗原
See all MARCH5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-32
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原理
- MARCH5 Antibody / Membrane-associated RING finger protein 5
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免疫原
- A portion of amino acids 4-32 from the human protein was used as the immunogen for this MARCH5 antibody.
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亚型
- Ig Fraction
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anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (AA 4-32), (N-Term) antibody
MARCH5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21862 unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (AA 1-95) antibodyMARCH5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (AA 1-95) antibodyMARCH5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (C-Term) antibodyMARCH5 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 豚鼠, 马, 兔, 小鸡, Bat, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (N-Term) antibodyMARCH5 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the MARCH5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MARCH5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))
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别名
- MARCH5
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背景
- Membrane-associated RING finger protein 5 (MARCH5), also known as MARCHF5, is involved in cellular processes that are essential for maintaining the homeostasis and integrity of the cell. It possesses a RING finger domain that allows it to function as an E3 ubiquitin ligase, mediating the ubiquitination and subsequent degradation of specific target proteins. One of the key functions of MARCH5 is its role in regulating the turnover of mitochondrial proteins. Studies have shown that MARCH5 targets a variety of mitochondrial proteins for ubiquitination, leading to their degradation by the proteasome. This process helps to maintain the quality control of mitochondria and ensures the proper functioning of these vital organelles. Furthermore, MARCH5 has been implicated in various cellular processes, including apoptosis, autophagy, and immune response. By targeting specific proteins for degradation, MARCH5 can regulate the signaling pathways that govern these processes, influencing cell survival, proliferation, and immunity. MARCH5 has also been linked to the development of certain diseases, such as Parkinson's disease and cancer. Dysregulation of MARCH5 expression or activity has been observed in these conditions.
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UniProt
- Q9NX47
抗原
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