GCLM 抗体 (AA 4-263)
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Quick Overview for GCLM 抗体 (AA 4-263) (ABIN7874664)
抗原
See all GCLM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-263
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原理
- GCLM Antibody / Glutamate-cysteine ligase regulatory subunit
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids D4-K263) was used as the immunogen for the GCLM antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the GCLM antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the GCLM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
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别名
- GCLM
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背景
- Glutamate-cysteine ligase regulatory subunit is an enzyme that in humans is encoded by the GCLM gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- P48507
抗原
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