ARHGEF12 抗体 (AA 4-254)
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Quick Overview for ARHGEF12 抗体 (AA 4-254) (ABIN7874663)
抗原
See all ARHGEF12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-254
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原理
- LARG Antibody / ARHGEF12
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids T4-S254) was used as the immunogen for the LARG antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the LARG antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the LARG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ARHGEF12 (rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12))
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别名
- LARG
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背景
- Rho guanine nucleotide exchange factor 12 is a protein that in humans is encoded by the ARHGEF12 gene. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q9NZN5
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途径
- Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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