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Caveolin-1 抗体 (AA 4-178)

The 小鼠 单克隆 anti-Caveolin-1 antibody (Clone 12C7) (ABIN7874659) specifically detects Caveolin-1 in WB, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7874659
发货至: 中国
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Quick Overview for Caveolin-1 抗体 (AA 4-178) (ABIN7874659)

抗原

See all Caveolin-1 (CAV1) 抗体
Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

适用

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宿主

  • 142
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小鼠

克隆类型

  • 100
  • 61
单克隆

标记

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This Caveolin-1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

12C7
  • 抗原表位

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    AA 4-178

    原理

    Caveolin-1 Antibody

    纯化方法

    Purified

    免疫原

    Amino acids G4-I178 from the human protein were used as the immunogen for the Caveolin-1 antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the Caveolin-1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Caveolin-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

    别名

    Caveolin-1

    背景

    CAV1( Caveolin-1) is a protein that in humans is encoded by the CAV1 gene. The CAV1 gene is mapped to 7q31.2. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms(alpha and beta) are encoded by a single transcript from this gene.

    UniProt

    Q03135

    途径

    Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
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