BCL9L 抗体 (AA 397-666)
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Quick Overview for BCL9L 抗体 (AA 397-666) (ABIN7874649)
抗原
See all BCL9L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 397-666
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原理
- BCL9L Antibody
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纯化方法
- Affinity purified
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免疫原
- Amino acids E397-A666 from the human protein were used as the immunogen for the BCL9L antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the BCL9L antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- Store the BCL9L antibody at -20oC.
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- BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))
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别名
- BCL9L
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背景
- B-cell CLL/lymphoma 9 like is a protein that in humans is encoded by the BCL9L gene. It is mapped to 11q23.3. Bcl-9 (B-cell lymphoma 9, also Protein legless homolog) is a transcriptional regulator that belongs to the Bcl-9 family of proteins. It is expressed in multiple tissues and serves to recruit Pygopus to the Wnt-pathway beta -catenin-TCF complex in the nucleus. Bcl-9 and Bcl-9-2 are considered evolutionary duplicates of Legless that perform the same task with different regulation. Human Bcl-9 is 1426 amino acids (aa) in length. It contains one phosphothreonine and three phosphoserine sites that have been identified so far, two poly-Pro regions (aa 514?517 and 970?973), and one poly-Ala segment (aa 900?903). There is one potential alternate start site at Met27, and a variant isoform exists that shows a four aa substitution for aa 1391?1426. Over aa 1009?1328, human Bcl-9 is 96 % aa identical to mouse Bcl-9.
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UniProt
- Q86UU0
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途径
- Stem Cell Maintenance
抗原
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