STAR 抗体 (AA 39-108)
Our Local Distributor
北京 101111
Quick Overview for STAR 抗体 (AA 39-108) (ABIN7874564)
抗原
See all STAR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 39-108
-
原理
- StAR Antibody / Steroidogenic acute regulatory protein
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- A portion of amino acids 39-108 from the human protein was used as the immunogen for this StAR antibody.
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the StAR antibody to be titered up or down for optimal performance.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the StAR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- STAR (Steroidogenic Acute Regulatory Protein (STAR))
-
别名
- StAR
-
背景
- Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
-
UniProt
- P49675
-
途径
- Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
抗原
-