AKAP12 抗体 (AA 387-1620)
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Quick Overview for AKAP12 抗体 (AA 387-1620) (ABIN7874549)
抗原
See all AKAP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 387-1620
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原理
- AKAP12 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant mouse protein (amino acids E387-H1620) was used as the immunogen for the AKAP12 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the AKAP12 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the AKAP12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
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别名
- AKAP12
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背景
- A-kinase anchor protein 12, also called AKAP250, is an enzyme that in humans is encoded by the AKAP12 gene. The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinase A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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UniProt
- Q9WTQ5
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途径
- cAMP Metabolic Process
抗原
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