Myosin VI 抗体 (AA 383-786)
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Quick Overview for Myosin VI 抗体 (AA 383-786) (ABIN7874533)
抗原
See all Myosin VI (MYO6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 383-786
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原理
- MYO6 Antibody / Unconventional Myosin-6
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (Q383-H786) was used as the immunogen for the MYO6 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MYO6 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MYO6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Myosin VI (MYO6)
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别名
- MYO6
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背景
- Unconventional myosin-VI, is a protein that in humans is coded for by MYO6. This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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UniProt
- Q9UM54
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途径
- Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization
抗原
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