MNT 抗体 (AA 381-564)
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Quick Overview for MNT 抗体 (AA 381-564) (ABIN7874523)
抗原
See all MNT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 381-564
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原理
- MNT Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids H381-N564) was used as the immunogen for the MNT antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MNT antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MNT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MNT (MNT, MAX Dimerization Protein (MNT))
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别名
- MNT
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背景
- MNT (Max's Next Tango) is a Max-binding protein that is encoded by the MNT gene. It is mapped to 17p13.3. The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.
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UniProt
- Q99583
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation
抗原
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