Desmoglein 3 抗体 (AA 379-491)
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北京 101111
Quick Overview for Desmoglein 3 抗体 (AA 379-491) (ABIN7874485)
抗原
See all Desmoglein 3 (DSG3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 379-491
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原理
- Desmoglein 3 Antibody / DSG3
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein (amino acids 379-491) was used as the immunogen for the Desmoglein 3 antibody.
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亚型
- IgG1, kappa
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anti-Desmoglein 3 (DSG3) (AA 55-159) antibody
DSG3 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6G2C11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 适用: 人 IHC 宿主: 小鼠 Monoclonal DSG3-2840 unconjugated
anti-Desmoglein 3 (DSG3) (AA 858-999) antibodyDSG3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 适用: 人 IHC 宿主: 小鼠 Monoclonal 543M unconjugated
anti-Desmoglein 3 (DSG3) (AA 50-75) antibodyDSG3 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 5G11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal DSG3-2796 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 适用: 人 IHC, ICC 宿主: 小鼠 Monoclonal BC11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 70-615) antibodyDSG3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal dilution of the Desmoglein 3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Desmoglein 3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Desmoglein 3 (DSG3)
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别名
- Desmoglein 3
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背景
- Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80 % ) and specificity (100 %) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.
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UniProt
- P32926
抗原
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