PI4KB 抗体 (AA 375-671)
Our Local Distributor
北京 101111
Quick Overview for PI4KB 抗体 (AA 375-671) (ABIN7874462)
抗原
See all PI4KB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 375-671
-
原理
- PI4KB Antibody / Phosphatidylinositol 4-kinase beta
-
纯化方法
- Antigen affinity chromatography
-
免疫原
- An E.coli-derived human recombinant protein (amino acids D375-D671) was used as the immunogen for the PI4KB antibody.
-
亚型
- IgG
-
-
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (AA 20-51), (N-Term) antibody
PI4KB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1676 unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (AA 519-548) antibodyPI4KB 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18563 unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (AA 731-828) antibodyPI4KB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B1 unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (Middle Region) antibodyPI4KB 适用: 人 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (N-Term) antibodyPI4KB 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (AA 755-804) antibodyPI4KB 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 兔, Cow, 豚鼠, 马, 非洲爪蟾, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (AA 251-300) antibodyPI4KB 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 兔, Cow, 豚鼠, 马, 非洲爪蟾, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (Internal Region) antibodyPI4KB 适用: 人 WB, ELISA, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB) (Middle Region) antibodyPI4KB 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 兔, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the PI4KB antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the PI4KB Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- PI4KB (Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB))
-
别名
- PI4KB
-
背景
- Phosphatidylinositol 4-kinase beta is an enzyme that in humans is encoded by the PI4KB gene. Inositol phospholipids have an important role in intracellular signaling in response to hormones, growth factors and neurotransmitters. Phosphatidylinositol 4-kinase phosphorylates phosphatidylinositol (PI) to phosphatidylinositol-4-phosphate (PIP). In a second step, PIP is further phosphorylated to phosphatidylinositol-4,5-bisphosphate (PIP2), and PIP2 is subsequently hydrolyzed by phospholipase C, producing the two intracellular second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI4K230, PI4K92 and PI4K55 are three PI4 kinase isoforms that have been characterized and classified according to their molecular weights of 230, 92 and 55 kD. Previously, PI4 kinases were classified into type II and III enzymes. All isoforms are located on distinct membranes and cellular compartments suggesting various tasks. PI4K230 is located at the endoplasmatic reticulum and outer membranes of mitochondria, PI4K92 at the Golgi apparatus and endoplasmatic reticulum, and PI4K55 at the plasma membrane and endosomes. PI4K230 is predominantly expressed in brain and moderately sensitive to wortmannin as well as specifically and irreversibly inhibited by cyclitol derivatives.
-
UniProt
- Q9UBF8
-
途径
- Inositol Metabolic Process
抗原
-
