SHROOM1 抗体 (AA 371-807)
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Quick Overview for SHROOM1 抗体 (AA 371-807) (ABIN7874429)
抗原
See all SHROOM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 371-807
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原理
- SHROOM1 Antibody / APXL2
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R371-D807) was used as the immunogen for the SHROOM1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SHROOM1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SHROOM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SHROOM1 (Shroom Family Member 1 (SHROOM1))
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别名
- SHROOM1
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背景
- SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.
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UniProt
- Q2M3G4
抗原
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