OB Cadherin 抗体 (AA 371-796)
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Quick Overview for OB Cadherin 抗体 (AA 371-796) (ABIN7874428)
抗原
See all OB Cadherin (CDH11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 371-796
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原理
- Cadherin 11 Antibody / CDH11 / OB-Cadherin
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纯化方法
- Affinity purified
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免疫原
- A human recombinant partial protein (amino acids K371-S796) was used as the immunogen for the Cadherin 11 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Cadherin 11 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Cadherin 11 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
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别名
- Cadherin 11
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背景
- Cadherin-11, also called Osteoblast cadherin or OB Cadherin, is a protein that in humans is encoded by the CDH11 gene. This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
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UniProt
- P55287
抗原
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