Cadherin-16 抗体 (AA 371-507)
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Quick Overview for Cadherin-16 抗体 (AA 371-507) (ABIN7874425)
抗原
See all Cadherin-16 (CDH16) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 371-507
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原理
- CDH16 Antibody / Cadherin 16 (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein (amino acids 371-507) was used as the immunogen for the CDH16 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the CDH16 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CDH16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Cadherin-16 (CDH16)
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别名
- CDH16
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背景
- This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin (also called CDH16 and Cadherin 16). Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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UniProt
- O75309
抗原
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