COX7A2L 抗体 (AA 37-65)
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Quick Overview for COX7A2L 抗体 (AA 37-65) (ABIN7874417)
抗原
See all COX7A2L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 37-65
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原理
- COX7A2L Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 37-65 from the human protein was used as the immunogen for the COX7A2L antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the COX7A2L antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the COX7A2L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))
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别名
- COX7A2L
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背景
- Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.
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UniProt
- O14548
抗原
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