Retinoblastoma Binding Protein 4 抗体 (AA 365-424)
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Quick Overview for Retinoblastoma Binding Protein 4 抗体 (AA 365-424) (ABIN7874340)
抗原
See all Retinoblastoma Binding Protein 4 (RBBP4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 365-424
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原理
- Zebrafish Rbbp4 Antibody / Retinoblastoma-binding protein 4
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Rbbp4 recombinant protein (amino acids E365-Q424) was used as the immunogen for the Zebrafish Rbbp4 antibody.
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亚型
- Ig Fraction
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anti-Retinoblastoma Binding Protein 4 (RBBP4) antibody
KD Validated RBBP4 适用: 人 WB, FACS, ICC, IF (p) 宿主: 兔 Monoclonal 24GB1240 unconjugated Recombinant Antibody
anti-Retinoblastoma Binding Protein 4 (RBBP4) (AA 1-425) antibodyRBBP4 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Retinoblastoma Binding Protein 4 (RBBP4) (AA 395-425), (C-Term) antibodyRBBP4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 9F3 unconjugated
anti-Retinoblastoma Binding Protein 4 (RBBP4) (AA 395-425), (C-Term) antibodyRBBP4 适用: 人, 小鼠, 大鼠 WB, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 4 (RBBP4) antibodyRBBP4 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 4 (RBBP4) (AA 316-426) antibodyRBBP4 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 4A5 unconjugated
anti-Retinoblastoma Binding Protein 4 (RBBP4) antibodyRBBP4 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Monoclonal 3E9 unconjugated Recombinant Antibody
anti-Retinoblastoma Binding Protein 4 (RBBP4) (AA 1-50) antibodyRBBP4 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 4 (RBBP4) (AA 1-426) antibodyRBBP4 适用: 人 WB, IHC, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Retinoblastoma Binding Protein 4 (RBBP4) (C-Term) antibodyRBBP4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Rbbp4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Rbbp4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Retinoblastoma Binding Protein 4 (RBBP4)
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别名
- Rbbp4
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背景
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Zebrafish Rbbp4, also known as retinoblastoma binding protein 4, is a chromatin associated protein that plays a crucial role in regulating gene expression by modifying chromatin structure. It is a member of the WD40 repeat protein family and is involved in the assembly and function of multiple chromatin remodeling and histone deacetylase complexes. Rbbp4 contributes to nucleosome remodeling and histone modification, processes that are essential for transcriptional regulation, DNA replication, and cell cycle progression.
Zebrafish Rbbp4 is an ortholog of the human RBBP4 protein, with a high level of sequence and functional conservation. The protein interacts with histone H4 and serves as a core component of complexes such as the nucleosome remodeling and deacetylase complex, also known as the NuRD complex. Through these interactions, Rbbp4 plays a vital role in controlling the accessibility of DNA for transcription factors and other regulatory proteins.
At present, there is no evidence of multiple isoforms of zebrafish Rbbp4 being identified, in contrast to some other chromatin associated proteins. Research on Rbbp4 in zebrafish provides insights into its roles during development, as chromatin remodeling is critical for processes such as cell differentiation, axis formation, and organ development.
Antibodies targeting zebrafish Rbbp4 protein are important tools for studies in epigenetic regulation, histone dynamics, and developmental biology. Given its orthology to human RBBP4, zebrafish Rbbp4 serves as a valuable model to study conserved mechanisms of chromatin remodeling and transcriptional regulation.
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UniProt
- Q6P3H7
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus
抗原
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