CNTNAP2 抗体 (AA 363-1159)
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Quick Overview for CNTNAP2 抗体 (AA 363-1159) (ABIN7874334)
抗原
See all CNTNAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 363-1159
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原理
- CASPR2 Antibody / CNTNAP2
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids N363-E1159) was used as the immunogen for the CASPR2 antibody.
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亚型
- IgG
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anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1-1331) antibody
CNTNAP2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1079-1106) antibodyCNTNAP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB22699 unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 801-900) antibodyCNTNAP2 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1-1331) antibodyCNTNAP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1315-1331), (Intracellular) antibodyCNTNAP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (Extracellular Domain) antibodyCNTNAP2 适用: 人 WB, IHC, IP, FM 宿主: 小鼠 Monoclonal S67-25 unconjugated
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应用备注
- Optimal dilution of the CASPR2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CASPR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
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别名
- CASPR2
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背景
- Contactin-associated protein-like 2 is a protein that in humans is encoded by the CNTNAP2 gene. This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5 % of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability.
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UniProt
- Q9UHC6
抗原
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