TTLL9 抗体 (AA 36-439)
The 兔 多克隆 anti-TTLL9 antibody is suitable to detect TTLL9 in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA 和 WB.
产品编号 ABIN7874319
发货至:
中国
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Quick Overview for TTLL9 抗体 (AA 36-439) (ABIN7874319)
抗原
See all TTLL9 抗体
TTLL9
(Tubulin tyrosine Ligase-Like Family, Member 9 (TTLL9))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This TTLL9 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 36-439
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原理
- TTLL9 Antibody / Tubulin tyrosine ligase-like protein 9
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纯化方法
- Immunogen affinity purified
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免疫原
- E.coli-derived human TTLL9 recombinant protein (Position: K36-S439) was used as the immunogen for the TTLL9 antibody.
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亚型
- IgG
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anti-Tubulin tyrosine Ligase-Like Family, Member 9 (TTLL9) (AA 1-230) antibody
TTLL9 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tubulin tyrosine Ligase-Like Family, Member 9 (TTLL9) (AA 36-439) antibodyTTLL9 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the TTLL9 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TTLL9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TTLL9 (Tubulin tyrosine Ligase-Like Family, Member 9 (TTLL9))
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别名
- TTLL9
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背景
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TTLL9 antibody detects Tubulin tyrosine ligase-like protein 9, encoded by the TTLL9 gene. Tubulin tyrosine ligase-like protein 9 is a member of the tubulin tyrosine ligase-like family of enzymes and is involved in post-translational modification of tubulin through polyglutamylation. TTLL9 antibody provides researchers with a reagent for studying microtubule regulation, ciliary function, and neuronal biology.
Tubulin tyrosine ligase-like protein 9 belongs to a large family of enzymes that regulate tubulin side chain modifications. Research using TTLL9 antibody has shown that it catalyzes polyglutamylation of tubulin tails, a modification that regulates microtubule interactions with molecular motors and associated proteins. This modification is essential for the structural and functional diversity of the microtubule cytoskeleton.
Studies with TTLL9 antibody have demonstrated that polyglutamylation mediated by TTLL9 is critical for ciliary function and neuronal signaling. In cilia, TTLL9 activity regulates motility and sensory reception, while in neurons, it influences axonal transport and synaptic function. These findings underscore its broad importance in cellular physiology.
Dysfunction of Tubulin tyrosine ligase-like protein 9 has been linked to ciliopathies and neurological disease. Research using TTLL9 antibody has shown that defects in polyglutamylation cause impaired ciliary motility, sensory dysfunction, and neurodegeneration. In addition, altered TTLL9 activity has been observed in certain cancers, suggesting roles in proliferation and cytoskeletal regulation.
TTLL9 antibody is widely applied in immunofluorescence, western blotting, and immunohistochemistry. Immunofluorescence highlights modified microtubule arrays, western blotting quantifies expression across tissues, and immunohistochemistry demonstrates localization in brain and ciliated tissues. These applications make TTLL9 antibody indispensable in microtubule research.
By supplying validated TTLL9 antibody reagents, NSJ Bioreagents supports studies into tubulin modification, neuronal function, and ciliary biology. Detection of Tubulin tyrosine ligase-like protein 9 provides researchers with insight into how post-translational modification regulates microtubule diversity and disease. -
UniProt
- Q3SXZ7
抗原
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