SOD3 抗体 (AA 36-101)
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Quick Overview for SOD3 抗体 (AA 36-101) (ABIN7874290)
抗原
See all SOD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 36-101
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原理
- Superoxide dismutase 3 Antibody / Sod3
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived mouse protein (amino acids V36-L101) was used as the immunogen for the Superoxide dismutase 3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Superoxide dismutase 3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Superoxide dismutase 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))
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别名
- Superoxide dismutase 3
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背景
- SOD3 (SUPEROXIDE DISMUTASE 3), also called SUPEROXIDE DISMUTASE, EXTRACELLULAR, EC-SOD, and Cu-Zn, is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. Hendrickson et al. (1990) mapped the SOD3 gene to 4pter-q21 by a study of somatic cell hybrids. Stern et al. (2003) narrowed the assignment to 4p15.3-p15.1 by somatic cell and radiation hybrid analysis, linkage mapping, and FISH. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.
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UniProt
- O09164
抗原
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