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Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体

This 小鼠 单克隆 antibody specifically detects Spectrin, Beta, Non-erythrocytic 2 in WB, IF 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7874273
发货至: 中国
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Quick Overview for Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体 (ABIN7874273)

抗原

See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体
Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

适用

  • 114
  • 36
  • 35
  • 1

宿主

  • 70
  • 44
小鼠

克隆类型

  • 103
  • 11
单克隆

标记

  • 43
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
非结合性

应用范围

  • 111
  • 76
  • 66
  • 64
  • 29
  • 23
  • 8
  • 6
  • 4
  • 4
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

SPTBN2-1778
  • 抗原表位

    • 101
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-475

    原理

    Spectrin beta III Antibody / SPTBN2 (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    Human recombinant partial protein corresponding to amino acids 356-475 was used as the immunogen for this Spectrin beta III antibody.

    亚型

    IgG1, kappa
  • 应用备注

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Spectrin beta III antibody to be titered up or down for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Spectrin beta III antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

    别名

    Spectrin beta III

    背景

    Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin and spectrin are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin I (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin III is highly homologous to both spectrin I and spectrin II. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta.

    UniProt

    O15020

    途径

    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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