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Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体

The 小鼠 单克隆 anti-Spectrin, Beta, Non-erythrocytic 2 antibody (Clone rSPTBN2-1778) (ABIN7874272) specifically detects Spectrin, Beta, Non-erythrocytic 2 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7874272
发货至: 中国
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Quick Overview for Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体 (ABIN7874272)

抗原

See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体
Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

抗体类型

Recombinant Antibody

适用

  • 114
  • 36
  • 35
  • 1

宿主

  • 70
  • 44
小鼠

克隆类型

  • 103
  • 11
单克隆

标记

  • 43
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
非结合性

应用范围

  • 111
  • 76
  • 66
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  • 29
  • 22
  • 8
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  • 4
  • 4
Western Blotting (WB), ELISA

克隆位点

RSPTBN2-1778
  • 抗原表位

    • 101
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-475

    原理

    Recombinant Spectrin beta III Antibody / SPTBN2

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 356-475) was used as the immunogen for the recombinant Spectrin beta III antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the recombinant Spectrin beta III antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant Spectrin beta III antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

    别名

    Spectrin beta III

    背景

    Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin and spectrin are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin I (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin III is highly homologous to both spectrin I and spectrin II. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.

    UniProt

    O15020

    途径

    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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