DDX39B 抗体 (AA 351-380)
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Quick Overview for DDX39B 抗体 (AA 351-380) (ABIN7874225)
抗原
See all DDX39B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 351-380
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原理
- DDX39B Antibody / UAP56
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 351-380 from the human protein was used as the immunogen for the DDX39B antibody.
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亚型
- Ig Fraction
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anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) antibody
DDX39B 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) (AA 319-428) antibodyDDX39B 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) (AA 1-250) antibodyDDX39B 适用: 人, 小鼠 IHC, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 2F5G7 unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) antibodyKO Validated DDX39B 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) antibodyDDX39B 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) (AA 2-251) antibodyDDX39B 适用: 人 IHC, WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) (C-Term) antibodyDDX39B 适用: 人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 猴, Pig, 兔, Bat, 小鸡, 犬 IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) antibody (Biotin)DDX39B 适用: 人 IHC, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) antibody (HRP)DDX39B 适用: 人 IHC, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal HRP
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) (N-Term) antibodyDDX39B 适用: 人, Cow, 山羊, 豚鼠, 马, 猴, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the DDX39B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the DDX39B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))
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别名
- DDX39B
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背景
- Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4. Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint. It has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity. Even with the stimulation of RNA, the ATPase activity is weak. It can only hydrolyze ATP but not other NTPs. The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA. However, ssRNA stimulates the ATPase activity much more strongly than dsRNA. It can unwind 5' or 3' overhangs or blunt end RNA duplexes in vitro. The ATPase and helicase activities are not influenced by U2AF2 and THOC4.
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UniProt
- Q13838
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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